# Intravenous Tobramycin Inhalation for Patients With Advanced Bronchiectasis With Pseudomonas aeruginosa Infection in Home Medical Care: A Report of Two Cases

**Authors:** Katsutoshi Ando

PMC · DOI: 10.7759/cureus.62726 · 2024-06-19

## TL;DR

Two patients with advanced bronchiectasis were successfully treated with inhaled tobramycin at home using simple tools.

## Contribution

A practical home-based method for administering inhaled tobramycin using common devices is proposed.

## Key findings

- Inhaled tobramycin was effective in treating Pseudomonas aeruginosa infection in home settings.
- Commercial eye drop containers and nebulizers enabled aseptic preparation and delivery of the drug.
- This approach offers a viable alternative to daily injections for home medical care patients.

## Abstract

Home medical care faces limitations in the number of doctor and nurse visits, availability of medical devices, and economic factors, making daily injections difficult for in-home patients. We describe two cases of advanced bronchiectasis with Pseudomonas aeruginosa infection treated with inhaled tobramycin in a home setting, demonstrating clinical effectiveness. Using commercially available empty eye drop containers to prepare an aseptic inhalation solution and nebulizers easily usable at home, our experience suggests that this could be a viable therapeutic alternative in home medical care.

## Linked entities

- **Chemicals:** tobramycin (PubChem CID 36294)
- **Diseases:** bronchiectasis (MONDO:0004822)

## Full-text entities

- **Diseases:** Pseudomonas aeruginosa Infection (MESH:D011552), Bronchiectasis (MESH:D001987)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11186675/full.md

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Source: https://tomesphere.com/paper/PMC11186675