Histological Remission of Eosinophilic Esophagitis Following Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myelogenous Leukemia
Gabriela Méndez, Theodor Griggs, Daniel Ludi, Cemal Yazici, Su Yeon Yeon
TL;DR
A man with eosinophilic esophagitis achieved full healing in his esophagus after a stem cell transplant for leukemia, suggesting a potential new treatment approach.
Contribution
This is the first reported case of histological remission of EoE following allogeneic HSCT.
Findings
A 54-year-old man with EoE achieved histological remission after allogeneic HSCT for AML.
The case suggests that HSCT may offer a curative option for EoE, though further studies are needed.
Abstract
Eosinophilic esophagitis (EoE) is an immune/antigen-mediated disease with an increasing incidence over the last decade. Clinicopathological remission can be achieved through different treatment options but often requires chronic therapy. To our knowledge, this is the first report of EoE wherein the patient (a 54-year-old man) achieved histological remission after allogeneic hematopoietic stem cell transplantation (HSCT) for acute myelogenous leukemia. Overall, despite the success of EoE treatment in this case, further studies are needed to establish allogeneic HSCT as a curative option for EoE.
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Taxonomy
TopicsEosinophilic Esophagitis · Eosinophilic Disorders and Syndromes · IL-33, ST2, and ILC Pathways