# Cryobiopsy for Secondary Pulmonary Alveolar Proteinosis

## TL;DR

This paper presents a case where transbronchial lung cryobiopsy successfully diagnosed secondary pulmonary alveolar proteinosis without complications.

## Contribution

The paper introduces the first reported use of TBLC for diagnosing SPAP, highlighting its utility and safety.

## Key findings

- TBLC provided sufficient tissue for diagnosing SPAP.
- No adverse events occurred during or after the procedure.
- TBLC is a viable diagnostic tool for SPAP, which is rarely reported.

## Abstract

Secondary pulmonary alveolar proteinosis (SPAP) is one of the diffuse parenchymal lung diseases, and the utility and safety of transbronchial lung cryobiopsy (TBLC) for diagnosing SPAP are unknown. A case of SPAP diagnosed by TBLC is presented. Specimens that were useful for diagnosis were collected, and there was no adverse event following TBLC. The usefulness of TBLC for interstitial lung disease has been widely reported, but there are few reports of SPAP. We present the clinical course of TBLC in the diagnosis of SPAP.