# Awareness and Attitude About Ototoxic Drugs Among Medical Doctors in Arar City, Saudi Arabia

## TL;DR

This study assessed how well doctors in Arar City, Saudi Arabia, understand the hearing-damaging effects of certain medications.

## Contribution

The study provides new insights into physicians' awareness and attitudes toward ototoxic drugs in a specific region of Saudi Arabia.

## Key findings

- Most participants had satisfactory knowledge about ototoxicity, especially regarding frusemide and aminoglycoside.
- Clinical experience significantly improved knowledge scores about ototoxic drugs.
- Acetaminophen's ototoxic effects were the least recognized among participants.

## Abstract

Objectives: The purpose of this study was to assess the awareness of ototoxicity among medical doctors in Arar City, Saudi Arabia.

Methods: This is a cross-sectional study based on a pre-formed validated questionnaire (Appendix) that included three sections covering participants’ demographic data (three questions), their attitudes (five questions), and knowledge (13 questions) regarding drug-induced ototoxicity.

Results: After obtaining their informed consent, 213 physicians from government and private sector health facilities in Arar were enrolled in the study. Interns and general practitioners represented 57.8% of the participants; consultants represented 17.8%. Only 71.8% of participants were interested in drug-induced ototoxicity, while 26.3% considered ototoxicity a rare complication. Approximately 90% of the participants were knowledgeable about the adverse effects of drugs on the vestibulocochlear system, and 26.7% reported having experienced cases of drug-induced ototoxicity in their practice. Participants showed an overall knowledge score about ototoxicity of 9.3±3.27 (out of 14). The knowledge score was significantly higher (p-value=0.0007) for participants with more years of clinical experience. The most widely known ototoxic drug for participants was frusemide (72.3%), followed by aminoglycoside (68.5%), while acetaminophen (44.1%) ototoxicity was the least known among participants.

Conclusion: Awareness of drug-induced ototoxicity is satisfactory among physicians in the Northern Borders region. However, workshops about all types of drugs with ototoxic effects and the main lines for the management of drug-induced ototoxicity are recommended to increase awareness.