# Predictability of Insulin Resistance Based on the Clinical Manifestations Among Male Medical Students of a Private College in Saudi Arabia

**Authors:** Yousria A Badawy, Ahmed H Almakrami, Abdullah J Alata, Emad Z Abujamea, Louai M Khaliifa

PMC · DOI: 10.7759/cureus.60327 · 2024-05-15

## TL;DR

This study found that skin tags, acanthosis nigricans, and acne are common signs of insulin resistance in male medical students in Saudi Arabia.

## Contribution

The study identifies specific dermatological and cognitive indicators of insulin resistance in a specific demographic group.

## Key findings

- Skin tags and acanthosis nigricans were statistically significantly correlated with waist circumference as an indicator of insulin resistance.
- Acne was the most common symptom in both high and normal waist circumference groups.
- Excessive day sleep and cognitive issues were commonly reported among participants.

## Abstract

Background

Numerous clinical signs and symptoms are thought to be associated with insulin resistance. The purpose of this study was to examine the prevalence of insulin resistance among male medical students attending a private Saudi Arabian institution, based on clinical indications.

Methods

A convenient non-probability sample consisting of 241 male medical students was used to conduct cross-sectional research. Each participant had an in-person interview as well as anthropometric measurements. The interview consisted of a questionnaire that was used to assess demographic data and clinical manifestations related to insulin resistance.

Results

The study demonstrated the connection between a few dermatological symptoms and waist circumference as an indicator of insulin resistance. In both the high and normal waist circumference groups, acne was the most common symptom. There was no correlation found between waist circumference and psoriasis, hidradenitis suppurativa, androgenic alopecia, alopecia areata, or vitiligo. Nevertheless, as an indicator of insulin resistance, waist circumference was statistically significantly correlated with both skin tags and acanthosis nigricans. Most students had excessive day sleep, foggy brains, struggled with planning and solving problems, and had a memory that became worse in the past few years. In addition, many students feel hungry even after eating some sweets and usually have extreme thirst.

Conclusion

Among medical students, skin tags, acanthosis nigricans, and acne were the most prevalent dermatological manifestations. Clinicians need to be aware that skin conditions, sleep difficulties throughout the day, changes in cognition, and food cravings might all be indicators of internal changes and/or illnesses such as diabetes and prediabetes.

## Linked entities

- **Diseases:** diabetes (MONDO:0005015), prediabetes (MONDO:0006920)

## Full-text entities

- **Diseases:** acanthosis nigricans (MESH:D000052), Insulin Resistance (MESH:D007333), androgenic alopecia (MESH:D000505), prediabetes (MESH:D011236), skin tags (MESH:C566904), psoriasis (MESH:D011565), sleep difficulties (MESH:D012893), alopecia areata (MESH:D000506), acne (MESH:D000152), hidradenitis suppurativa (MESH:D017497), diabetes (MESH:D003920), skin conditions (MESH:D012871), vitiligo (MESH:D014820)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC11177330