# Acute post-renal kidney graft dysfunction due to cytomegalovirus-positive nephrogenic adenoma—case report and review of the literature

**Authors:** Nicola Hosek, Matteo Montani, Laila-Yasmin Mani

PMC · DOI: 10.3389/fmed.2024.1394028 · Frontiers in Medicine · 2024-05-29

## TL;DR

A kidney transplant recipient developed acute graft dysfunction due to a CMV-positive ureteral tumor, suggesting a possible link between CMV and this rare condition.

## Contribution

Reports a rare case of CMV-positive nephrogenic adenoma causing post-renal dysfunction in a kidney transplant recipient.

## Key findings

- A 33-year-old kidney transplant recipient experienced acute graft dysfunction due to a CMV-positive ureteral nephrogenic adenoma.
- This is the second reported case linking CMV with nephrogenic adenoma in transplant recipients.
- The causal relationship between CMV and nephrogenic adenoma remains to be confirmed.

## Abstract

Tissue-invasive cytomegalovirus (CMV) disease represents a well-recognized complication after kidney transplantation. However, direct involvement of the urogenital tract and CMV-ureteritis occur less frequently. Nephrogenic adenomas are benign lesions of the urinary tract preferentially reported in kidney transplant recipients. We herein report a second case of a 33-year-old male kidney transplant recipient with acute post-renal allograft dysfunction due to CMV-positive ureteral nephrogenic adenoma. A causal connection might be suspected but remains to be proven.

## Linked entities

- **Diseases:** nephrogenic adenoma (MONDO:0004191)

## Full-text entities

- **Diseases:** Acute post-renal kidney graft dysfunction (MESH:D058186), CMV- (MESH:D003586), post-renal allograft dysfunction (MESH:D007674), Nephrogenic adenomas (MESH:D000236), ureteritis (MESH:D014515)
- **Species:** Cytomegalovirus (genus) [taxon 10358]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC11175655/full.md

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11175655/full.md

## References

43 references — full list in the complete paper: https://tomesphere.com/paper/PMC11175655/full.md

---
Source: https://tomesphere.com/paper/PMC11175655