# Giant complete hydatidiform mole: a case report and review of the literature

## TL;DR

This paper reports a rare case of a large hydatidiform mole in a young woman successfully treated with conservative methods.

## Contribution

The novelty lies in demonstrating that conservative treatment can be effective for giant hydatidiform moles, even in young patients.

## Key findings

- A 20-year-old patient with a 22 cm hydatidiform mole was treated with surgical curettage.
- Conservative treatment was effective despite the mole's large size and the patient's young age.
- The case supports considering conservative approaches for fertility preservation in gestational trophoblastic disease.

## Abstract

This case describes the youngest patient documented in the literature who presented with a giant hydatidiform mole, effectively addressed through conservative treatment.

Our department received a 20-year-old Caucasian patient who was admitted due to significant metrorrhagia in an undisclosed pregnancy. During examination, we identified a massive, highly vascularized hydatidiform mole measuring 22 cm (cm). We performed a surgical dilatation and curettage. The anatomopathological findings confirmed the presence of a complete hydatidiform mole (CHM). Following the established guidelines, we conducted weekly monitoring of human chorionic gonadotropin (hCG). Unfortunately, the patient discontinued the follow-up and became pregnant again before achieving hCG negativation.

This case suggests that conservative treatment is a viable option regardless of the size of gestational trophoblastic disease (GTD), especially when the preservation of fertility is a crucial consideration, as effectively demonstrated in our case.