# Non-squamous Cancers of the Larynx

**Authors:** H. Bengu Cobanoglu, Erdal Rahman Koprucu

PMC · DOI: 10.1007/s11912-024-01535-4 · Current Oncology Reports · 2024-04-26

## TL;DR

This review discusses rare non-squamous laryngeal cancers, their symptoms, diagnosis, and treatment approaches.

## Contribution

The paper provides an updated overview of non-squamous laryngeal tumors and their treatment strategies.

## Key findings

- Non-squamous laryngeal tumors often present non-specific symptoms and are diagnosed at advanced stages.
- Treatment varies based on histopathological subtypes, which are as important as tumor stage.
- Common subtypes include salivary gland tumors, neuroendocrine carcinomas, and sarcomas.

## Abstract

Although non-squamous tumors of the larynx are really rare, they may not always be viewed from the same perspective in the multidisciplinary treatment approach once the diagnosis is made. In this review, non-squamous tumors of the larynx and current approaches in treatment will be discussed.

When the studies and meta-analyses presented in the last 5 years are evaluated, it is seen that these tumors usually show non-specific symptoms. Due to their submucosal location, the stage of the disease at the time of diagnosis is often advanced. In the literature, treatment may vary in these particular cases.

The majority of non-squamous tumors of the larynx includes minor salivary gland tumors, neuroendocrine carcinomas, sarcomas, cartilage tumors, and malignant melanomas. Once treating a patient with these diagnoses, it should be kept in mind that the histopathological subtype is almost as important as the stage of the tumor.

## Full-text entities

- **Diseases:** neuroendocrine carcinomas (MESH:D018278), cartilage tumors (MESH:D002357), Non-squamous Cancers of (MESH:D018307), sarcomas (MESH:D012509), non-squamous tumors of the larynx (MESH:D000077195), tumor (MESH:D009369), malignant melanomas (MESH:D008545), salivary gland tumors (MESH:D012468)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

104 references — full list in the complete paper: https://tomesphere.com/paper/PMC11168984/full.md

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Source: https://tomesphere.com/paper/PMC11168984