This paper is marked retracted in the scholarly record (OpenAlex). Interpret its findings with caution.
Retraction: Human Epididymis Protein-4 (HE-4): A Novel Cross-Class Protease Inhibitor
Abstract
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsProtein Degradation and Inhibitors · Ubiquitin and proteasome pathways · Histone Deacetylase Inhibitors Research
Following the publication of this article [1], concerns were raised regarding images in Figures 1 and 7. Specifically,
In response to the above concerns, the corresponding author acknowledged that there are similarities but refuted that the indicated areas are identical. Images and alternative experimental results provided in support of these figures did not resolve the concerns.
In light of the concerns affecting multiple figure panels that question the integrity of these data, the PLOS ONE Editors retract this article.
NC, AKT, and SY did not agree with the retraction and stand by the article’s findings. MS, SD, and SS either did not respond directly or could not be reached.
The reference list from the paper itself. Each links out to its DOI / PubMed record.