Thyroxine Therapy Treating Infertility and Pituitary Tumor: Primary Hypothyroidism Leading to Pituitary Hyperplasia

TL;DR

A young patient with pituitary hyperplasia due to hypothyroidism showed improvement after thyroxine treatment, with reduced symptoms and tumor size.

Contribution

Demonstrates successful thyroxine therapy in treating infertility and pituitary tumor caused by primary hypothyroidism.

Findings

The patient experienced symptom improvement and normalized thyroid profile after thyroxine treatment.

Follow-up MRI showed a reduction in the size of the pituitary lesion.

Primary hypothyroidism was identified as the underlying cause of pituitary hyperplasia.

Abstract

Pituitary lesions can occur as a consequence of primary hypothyroidism and the biochemical imbalance associated with it, making its diagnosis a challenging task necessitating a thorough patient assessment by the treating physicians. We describe a young patient with pituitary hyperplasia due to primary hypothyroidism who presented with complaints of menstrual irregularities and weight gain. The patient was treated with thyroxine (T4) for primary hypothyroidism. The patient reported improvement in her symptoms along with the normalization of thyroid profile and interval reduction in the size of pituitary lesion on follow-up MRI scan.

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