# Prediction of low-addition segmented refractive intraocular lens position and deviation using anterior-segment optical coherence tomography

**Authors:** Norihiro Mita, Mai Yamazaki, Yusuke Seki, Yu Sasaki, Eri Shibuya, Tsuyoshi Mito, Natsuko Hatsusaka, Eri Kubo, Hiroshi Sasaki

PMC · DOI: 10.1371/journal.pone.0305076 · PLOS ONE · 2024-06-10

## TL;DR

This study develops a formula to predict the position and deviation of a specific type of intraocular lens after cataract surgery using optical coherence tomography.

## Contribution

A novel predictive formula for postoperative intraocular lens position and deviation using anterior-segment optical coherence tomography.

## Key findings

- A predictive formula was developed for anterior chamber depth, tilt, and decentration of low-added segmented refractive intraocular lenses.
- The formula showed significant correlations with measured postoperative values in a validation group.
- The findings suggest improved accuracy in predicting intraocular lens adaptation and postoperative refractive outcomes.

## Abstract

This study aimed to develop and analyze the accuracy of predictive formulae for postoperative anterior chamber depth, tilt, and decentration of low-added-segment refractive intraocular lenses. This single-center, retrospective, observational study included the right eyes of 96 patients (mean age: 72.43 ± 6.58 years), who underwent a cataract surgery with implantation of a low-added segmented refractive intraocular lens at the Medical University Hospital between July 2019 and January 2021, and were followed up for more than 1 month postoperatively. The participants were divided into an estimation group to create a prediction formula and a validation group to verify the accuracy of the formula. Anterior segment optical coherence tomography (CASIA 2, Tomey Corporation, Japan) and swept-source optical coherence tomography biometry (IOL Master 700, Carl Zeiss Meditec AG) were used to measure the anterior ocular components. A predictive formula was devised for postoperative anterior chamber depth, intraocular lens tilt, and intraocular lens decentration (p <0.01) in the estimation group. A significant positive correlation was observed between the estimated values calculated using the prediction formula and the measured values for postoperative anterior chamber depth (r = 0.792), amount of intraocular lens tilt (r = 0.610), direction of intraocular lens tilt (r = 0.668), and amount of intraocular lens decentration (r = 0.431) (p < 0.01) in the validation group. In conclusion, our findings reveal that predicting the position of the low-added segmented refractive intraocular lens enables the prognosis of postoperative refractive values with a greater accuracy in determining the intraocular lens adaptation.

## Full-text entities

- **Diseases:** cataract (MESH:D002386)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

39 references — full list in the complete paper: https://tomesphere.com/paper/PMC11164357/full.md

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Source: https://tomesphere.com/paper/PMC11164357