# The effect of an intraoperative patient-specific, surgery-specific haemodynamic algorithm in improving textbook outcomes for hepatobiliary–pancreatic surgery: a multicentre retrospective study

**Authors:** Bradly Carp, Laurence Weinberg, Luke R. Fletcher, Jake V. Hinton, Adam Cohen, Hugh Slifirski, Peter Le, Stephen Woodford, Shervin Tosif, David Liu, Vijaragavan Muralidharan, Marcos V. Perini, Mehrdad Nikfarjam, Dong-Kyu Lee

PMC · DOI: 10.3389/fsurg.2024.1353143 · Frontiers in Surgery · 2024-05-27

## TL;DR

A study found that using a personalized haemodynamic algorithm during hepatobiliary-pancreatic surgery improved patient outcomes compared to standard care.

## Contribution

This study evaluates a novel patient-specific haemodynamic algorithm's impact on achieving textbook surgical outcomes in hepatobiliary-pancreatic surgery.

## Key findings

- Patients using the AHDM algorithm had a higher textbook outcome rate (67.8%) compared to usual care (54.8%).
- AHDM was associated with fewer complications and shorter hospital stays.
- There was no significant difference in readmission or mortality rates between the groups.

## Abstract

The concept of a “textbook outcome” is emerging as a metric for ideal surgical outcomes. We aimed to evaluate the impact of an advanced haemodynamic monitoring (AHDM) algorithm on achieving a textbook outcome in patients undergoing hepatobiliary–pancreatic surgery.

This retrospective, multicentre observational study was conducted across private and public teaching sectors in Victoria, Australia. We studied patients managed by a patient-specific, surgery-specific haemodynamic algorithm or via usual care. The primary outcome was the effect of using a patient-specific, surgery-specific AHDM algorithm for achieving a textbook outcome, with adjustment using propensity score matching. The textbook outcome criteria were defined according to the International Expert Delphi Consensus on Defining Textbook Outcome in Liver Surgery and Nationwide Analysis of a Novel Quality Measure in Pancreatic Surgery.

Of the 780 weighted cases, 477 (61.2%, 95% CI: 57.7%–64.6%) achieved the textbook outcome. Patients in the AHDM group had a higher rate of textbook outcomes [n = 259 (67.8%)] than those in the Usual care group [n = 218 (54.8%); p < 0.001, estimated odds ratio (95% CI) 1.74 (1.30–2.33)]. The AHDM group had a lower rate of surgery-specific complications, severe complications, and a shorter hospital length of stay (LOS) [OR 2.34 (95% CI: 1.30–4.21), 1.79 (95% CI: 1.12–2.85), and 1.83 (95% CI: 1.35–2.46), respectively]. There was no significant difference between the groups for hospital readmission and mortality.

AHDM use was associated with improved outcomes, supporting its integration in hepatobiliary–pancreatic surgery. Prospective trials are warranted to further evaluate the impact of this AHDM algorithm on achieving a textbook impact on long-term outcomes.

## Full-text entities

- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

43 references — full list in the complete paper: https://tomesphere.com/paper/PMC11163073/full.md

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Source: https://tomesphere.com/paper/PMC11163073