# A Case Report of Subacute Infective Endocarditis Presenting With Extreme Weight Loss, Aortic Regurgitation, and Splenic Infarct

**Authors:** Austin Rahman, Patrick Rogers, Joshua B Piasecki, John Frederick

PMC · DOI: 10.7759/cureus.59866 · 2024-05-08

## TL;DR

This case report details a middle-aged man with subacute infective endocarditis who experienced significant weight loss, aortic regurgitation, and a splenic infarct.

## Contribution

The case highlights the varied and complex presentation of infective endocarditis, emphasizing its diagnostic challenges.

## Key findings

- The patient exhibited extreme weight loss, aortic regurgitation, and a splenic infarct as symptoms of IE.
- The case underscores the importance of considering IE in patients with unexplained systemic symptoms.
- It illustrates the broad diagnostic criteria and variable clinical manifestations of infective endocarditis.

## Abstract

We present an insightful case of a middle-aged male who presented to the emergency department (ED) with complaints of excessive weight loss, accompanied by shortness of breath and vomiting. Consequently, this case explores many facets of the pathophysiology of infective endocarditis (IE), including but not limited to the most heavily implicated microorganisms, symptoms, predispositions, and disease outcomes. IE is a pathology of variable presentation with uniquely extensive diagnostic criteria, making it a fascinating topic of medical discussion.

## Linked entities

- **Diseases:** infective endocarditis (MONDO:0000565)

## Full-text entities

- **Diseases:** vomiting (MESH:D014839), Weight Loss (MESH:D015431), IE (MESH:D004696), Splenic Infarct (MESH:D013159), shortness of breath (MESH:D004417)

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11157464/full.md

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Source: https://tomesphere.com/paper/PMC11157464