HOW I DO IT: Cushing’s disease—selective adenomectomy via an endoscopic transsphenoidal approach

TL;DR

This paper describes a surgical technique for removing pituitary tumors causing Cushing’s disease using an endoscopic transsphenoidal approach.

Contribution

The paper presents a detailed demonstration of selective adenomectomy using endoscopic techniques for Cushing’s disease.

Findings

Endoscopic transsphenoidal surgery provides a magnified view for precise tumor removal.

This approach increases the likelihood of achieving a complete resection and cure for patients.

A multidisciplinary approach is essential for successful treatment of Cushing’s disease.

Abstract

An ACTH-secreting pituitary adenoma is the most common cause of excessive endogenous glucocorticoid production resulting in Cushing’s Syndrome. A multidisciplinary approach is paramount. Selective adenomectomy is the treatment of choice.

Endoscopic transnasal transsphenoidal approach to the tumour, along with techniques for resection, are demonstrated.

Endoscopic transsphenoidal approaches with its magnified view of the pituitary gland allows precise microsurgical dissection during selective adenomectomy. This technique increases the possibility of proving a gross total resection, leading to clinical and biochemical cure in these patients.

The online version contains supplementary material available at 10.1007/s00701-024-06078-y.

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