Ischemic Stroke Outcome Predicted by Serum Albumin Levels

TL;DR

This study investigated whether blood albumin levels can predict outcomes in patients who had an ischemic stroke but found no significant correlation.

Contribution

The study challenges existing assumptions by showing no correlation between serum albumin levels and stroke outcomes.

Findings

Serum albumin levels did not correlate with outcomes measured by the modified Rankin Scale.

No association was found between serum albumin and NIHSS scores in stroke patients.

The results contradict previous assumptions about albumin's role in stroke prognosis.

Abstract

Objective and aim: This research aims to assess the predictive importance of serum albumin levels in individuals who have recently experienced an acute ischemic stroke and to establish a correlation between these two variables.

Materials and methods: A prospective hospital-based investigation with 50 participants was conducted after receiving ethical approval from Sunshine Hospital, Hyderabad, India. Patients older than 18 years old who had radiological or clinical evidence of having suffered an acute ischemic stroke were considered for participation in the research.

Results: Albumin levels in the blood are typically about 3.6 g/dL. One patient between the ages of 46 and 55 had low serum albumin levels. Many people in both groups had albumin levels of about 4.4. Serum albumin concentration was measured using the modified Rankin Scale (mRS). After one week and three months, 32 patients had mRS values of less than three, whereas 16 had mRS values of greater than three-one; the individual presented with an mRS value over 3, as well as a blood albumin level below 3.5. The p-value ended up being 0.428. No link could be supported by the statistical evidence identified. P = 0.249 indicated no association between serum albumin and National Institutes of Health Stroke Scale (NIHSS) scores. According to the findings of this inquiry, there is no correlation between the amounts of albumin in the blood and the NIHSS scores.

Conclusion: This study did not find a correlation between higher blood albumin levels and a worse outcome after an ischemic stroke. It contradicts the corpus of current knowledge.