# Prostate specific membrane antigen PET avidity in a granular cell tumour of the left supraspinatus muscle: a case report

**Authors:** Michael T Hsieh, Farokh Fargah, Abdul Rahim Mohd Tahir, Ngo Tue Le, Thomas P Shakespeare

PMC · DOI: 10.1093/bjrcr/uaae015 · 2024-05-29

## TL;DR

A rare tumor in a man's shoulder showed high uptake in a prostate cancer imaging test, marking the first known case of this kind.

## Contribution

This is the first reported case of PSMA-PET avidity in a granular cell tumor.

## Key findings

- A PSMA-avid lesion in the left supraspinatus muscle was identified in a 60-year-old male.
- The lesion was confirmed as a granular cell tumor through biopsy.

## Abstract

Granular cell tumour is a rare, mostly benign, soft tissue, neuroectodermal tumour, most commonly seen in the skin and peripheral soft tissue. There are no publications to date of PSMA-PET avidity in a granular cell tumour. In this 60 year old male, staging PSMA-PET for a localized intermediate risk prostate cancer incidentally identified a PSMA-avid left supraspinatus lesion, which was subsequently biopsy-proven as a granular cell tumour. We present the first case of PSMA-avid granular cell tumour and add to the growing literature documenting PSMA-PET avidity in benign and malignant lesions apart from prostate cancer.

## Linked entities

- **Diseases:** prostate cancer (MONDO:0005159)

## Full-text entities

- **Genes:** FOLH1 (folate hydrolase 1) [NCBI Gene 2346] {aka FGCP, FOLH, GCP2, GCPII, NAALAD1, PSM}
- **Diseases:** benign (MESH:D009369), prostate cancer (MESH:D011471), Granular cell tumour (MESH:D000230), lesions (MESH:D009059), neuroectodermal tumour (MESH:D017599)

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11153832/full.md

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Source: https://tomesphere.com/paper/PMC11153832