# First person – Niki Jalava

## TL;DR

This paper discusses how high glucose levels affect osteoblasts, focusing on transcriptional changes in bone cells under hyperglycemic conditions.

## Contribution

The study reveals unique transcriptional responses in osteoblasts to both short- and long-term high glucose exposure.

## Key findings

- Short-term high glucose exposure alters specific gene expressions in osteoblasts.
- Long-term exposure leads to distinct transcriptional changes compared to short-term effects.

## Abstract

First Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping researchers promote themselves alongside their papers. Niki Jalava is first author on ‘
Short- and long-term exposure to high glucose induce unique transcriptional changes in osteoblasts in vitro’, published in BiO. Niki is a doctoral researcher in the lab of Kaisa Ivaska at University of Turku, Institute of Biomedicine, Finland, investigating hyperglycemia and obesity on the bone-secreted proteins and intertissue communication.