# Giant cell-rich osteosarcoma of the lumbar spine – A rare entity

**Authors:** Tushar Kalekar, Ojasvi Sharma, Sayali Paidlewar, Ankita Pandey, Eshan C. Durgi

PMC · DOI: 10.4102/sajr.v28i1.2839 · 2024-05-09

## TL;DR

This paper reports a rare case of giant cell-rich osteosarcoma in the lumbar spine, highlighting its diagnostic challenges and treatment risks.

## Contribution

The novelty lies in presenting a rare case of GCRO in the lumbar spine with a focus on its diagnostic and surgical challenges.

## Key findings

- GCRO is difficult to distinguish from malignant giant cell tumour, affecting prognosis and management.
- Surgical excision in the lumbar spine poses increased risks due to its distinctive anatomy.

## Abstract

Giant cell-rich osteosarcoma (GCRO) is a rare variant of osteosarcoma. A significant diagnostic hurdle is presented by the lesion’s uncommon appearance on histopathology. This report presents a case of a 59-year-old female patient diagnosed with GCRO.

While it is extremely difficult to distinguish GCRO from malignant giant cell tumour, it is important to do so because of the difference in prognosis and management. Distinctive anatomy of the lumbar spine increases the risks associated with surgical excision.

## Full-text entities

- **Diseases:** GCRO (MESH:D018286), osteosarcoma (MESH:D012516), malignant giant cell tumour (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11151400/full.md

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Source: https://tomesphere.com/paper/PMC11151400