# Topical gabapentin and its relation to cutaneous innervation in symptomatic lymphocytic primary cicatricial alopecia

## TL;DR

This pilot study tested topical gabapentin for symptom relief in a skin condition called lymphocytic primary cicatricial alopecia.

## Contribution

The study explores the novel use of topical gabapentin for managing symptoms in a specific type of hair loss condition.

## Key findings

- Topical gabapentin significantly reduced symptoms in participants.
- No significant changes in nerve fibre density or neuropeptide expression were observed.

## Abstract

In this pilot study, participants with symptomatic lymphocytic primary cicatricial alopecia applied 6% topical gabapentin solution twice daily to affected areas for 12 weeks. There was a significant reduction in symptoms, but no pronounced effect on nerve fibre density or neuropeptide expression.