# Non-chronic kidney disease-induced calciphylaxis: a rare case report

**Authors:** Drake Giese, Katherine Ernste, Geethu Jnaneswaran, Ali Elkhedr

PMC · DOI: 10.1093/jscr/rjae404 · Journal of Surgical Case Reports · 2024-06-04

## TL;DR

This case report describes a rare instance of calciphylaxis in a patient without chronic kidney disease or dialysis history.

## Contribution

The novelty lies in presenting calciphylaxis in a non-end-stage renal disease patient and the challenges faced with standard treatment.

## Key findings

- Calciphylaxis occurred in a patient without end-stage renal disease or dialysis history.
- Sodium thiosulfate treatment was ineffective due to metabolic complications.

## Abstract

Calciphylaxis is a disorder causing ischemic skin necrosis, typically associated with end-stage renal disease or those receiving dialysis. Occurrence is rare in those without end-stage renal disease, and treatment options are limited. This case report describes a patient with calciphylaxis without end-stage renal disease or history of dialysis. Treatment with sodium thiosulfate, a first line option, had to be stopped due to metabolic derangements, limiting the healing process. Diagnosis and treatment of this rare disorder are important to prevent further complications that may result.

## Linked entities

- **Chemicals:** sodium thiosulfate (PubChem CID 24477)
- **Diseases:** calciphylaxis (MONDO:0017215), end-stage renal disease (MONDO:0004375)

## Full-text entities

- **Diseases:** Non-chronic kidney disease (MESH:D051436), skin necrosis (MESH:D012871), Calciphylaxis (MESH:D002115), ischemic (MESH:D002545), end-stage renal disease (MESH:D007676), metabolic derangements (MESH:D008659)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11149559/full.md

## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC11149559/full.md

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Source: https://tomesphere.com/paper/PMC11149559