# Awake Craniotomy for a Frontal Astrocytoma: A Case Report

**Authors:** Vladislav Velchev, Stefan Burev, Dilyan Ferdinandov, Deyan Popov, Petra Vasileva, Stela Petrova, Petar-Preslav Petrov, Remzi R Hyusein, Plamen Penchev

PMC · DOI: 10.7759/cureus.59667 · Cureus · 2024-05-05

## TL;DR

This case report describes a successful awake craniotomy with neuronavigation to remove a frontal glioma while preserving critical brain functions.

## Contribution

The paper highlights the effectiveness of awake craniotomy with neuronavigation for frontal low-grade glioma removal.

## Key findings

- Awake craniotomy with neuronavigation enabled total tumor excision without surgery-related complications.
- The patient retained motor and speech functions post-surgery and was discharged on the fifth day.
- Awake craniotomy is presented as the safest surgical option for frontal low-grade gliomas.

## Abstract

Awake craniotomy is a surgical procedure that has been gaining significance over the past decades. Neuronavigation is an intraoperative technology that locates tumors and monitors the brain cortex during awake craniotomy. The presence of cerebral low-grade gliomas in the frontal lobe creates a risk of affecting vital centers of the brain cortex during surgery. We present a clinical case of a 42-year-old male patient who entered the neurosurgery clinic with a clinical manifestation of headache for two months. MRI showed evidence of the recurrence of a left frontal glioma. Differential diagnoses of frontal gliomas include metastases, abscesses, and cysts. The pathophysiologic background of the disease is the mutation of neuroglial cells, which leads to an abnormal and uncontrollable proliferation. Under sleep-awake anesthesia, operative treatment was performed through left frontal awake craniotomy under neuronavigation. As a result, a total excision was achieved. Motor functions of the right limbs and speech have been preserved. The patient was mobilized on the day after the intervention. Surgery-related complications were not observed. The patient had relief from the symptoms and was discharged on the fifth day. Awake craniotomy combined with neuronavigation was the most efficient and the least harmful method for the excision of the tumor. For low-grade gliomas localized in the frontal area of the encephalon, awake craniotomy is the only secure option for surgery.

## Linked entities

- **Diseases:** astrocytoma (MONDO:0019781), glioma (MONDO:0021042)

## Full-text entities

- **Diseases:** cysts (MESH:D003560), metastases (MESH:D009362), frontal gliomas (MESH:D005910), headache (MESH:D006261), abscesses (MESH:D000038), tumor (MESH:D009369), Frontal Astrocytoma (MESH:D001254)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11149057/full.md

## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC11149057/full.md

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Source: https://tomesphere.com/paper/PMC11149057