# A Symptomatic Mucinous Cystic Neoplasm of the Mesentery: A Case Report

**Authors:** Maya Amy, Sanford E Roberts, Maria F Arisi, Robin Collingwood, Lillias Maguire

PMC · DOI: 10.7759/cureus.59660 · Cureus · 2024-05-05

## TL;DR

A rare case of a mucinous cystic tumor in the mesentery was successfully diagnosed and surgically removed from a 68-year-old woman.

## Contribution

This case report highlights the unusual occurrence of a mucinous cystic neoplasm in the mesentery and its successful surgical management.

## Key findings

- A 12 cm mucinous cystic neoplasm was found in the sigmoid mesentery of a 68-year-old woman.
- Histopathological and immunohistochemical analyses confirmed the diagnosis of a mucinous cystic neoplasm.
- The patient underwent successful resection and recovery, with no evidence of invasive carcinoma.

## Abstract

Mucinous cystic neoplasms (MCNs) are rare tumors primarily observed in the pancreas but occasionally found in other locations such as the retroperitoneum, ovary, liver, and spleen. These neoplasms are histologically classified based on the degree of dysplasia, with some associated with invasive carcinoma. Colorectal surgeons infrequently encounter MCNs. Mesenteric MCNs pose a diagnostic challenge secondary to their atypical location, subtle histology, and lack of specific biochemical markers. In this context, we present a case involving a 68-year-old female who initially presented with an assumed ovarian mass. Subsequent exploration revealed a 12 cm MCN situated in the sigmoid mesentery, a location seldom associated with these tumors. The patient underwent laparotomy with successful resection and recovery. Histopathological analysis confirmed the neoplasm's mucinous epithelium with a complex papillary architecture. Immunohistochemical staining supported the diagnosis, revealing positivity for CK7, SATB2, and CDX2.

## Linked entities

- **Proteins:** KRT7 (keratin 7), SATB2 (SATB homeobox 2), CDX2 (caudal type homeobox 2)
- **Diseases:** mucinous cystic neoplasm (MONDO:0044879), invasive carcinoma (MONDO:0040677)

## Full-text entities

- **Genes:** SATB2 (SATB homeobox 2) [NCBI Gene 23314] {aka C2DELq32q33, DEL2Q32Q33, GLSS}, KRT7 (keratin 7) [NCBI Gene 3855] {aka CK7, K2C7, K7, SCL}, CDX2 (caudal type homeobox 2) [NCBI Gene 1045] {aka CDX-3, CDX2/AS, CDX3}
- **Diseases:** dysplasia (MESH:D015792), neoplasm (MESH:D009369), invasive carcinoma (MESH:D009361), MCNs (MESH:D018297), mucinous (MESH:D002288), ovarian mass (MESH:D010049)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC11148626/full.md

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11148626/full.md

## References

6 references — full list in the complete paper: https://tomesphere.com/paper/PMC11148626/full.md

---
Source: https://tomesphere.com/paper/PMC11148626