# Specific pelvic shape in patients with developmental dysplasia of the hip on 3D morphometric homologous model analysis

**Authors:** Yui Sasaki, Daisuke Suzuki, Ryo Tokita, Hiroyuki Takashima, Hirofumi Matsumura, Satoshi Nagoya, Barry Kweh, Barry Kweh, Barry Kweh

PMC · DOI: 10.1371/journal.pone.0300938 · PLOS ONE · 2024-06-03

## TL;DR

This study identifies specific pelvic shape differences in patients with developmental dysplasia of the hip using 3D morphometric analysis.

## Contribution

A novel 3D morphometric approach using template-fitting and principal component analysis to identify pelvic shape differences in DDH patients.

## Key findings

- The first principal component showed decreased coxal inclination in both coronal and horizontal planes in DDH patients.
- The third principal component was linked to sacral inclination changes in the sagittal plane.
- The sixth principal component indicated narrowing of the superior part of the pelvis in DDH patients.

## Abstract

To clarify the morphological factors of the pelvis in patients with developmental dysplasia of the hip (DDH), three-dimensional (3D) pelvic morphology was analyzed using a template-fitting technique.

Three-dimensional pelvic data of 50 patients with DDH (DDH group) and 3D pelvic data of 50 patients without obvious pelvic deformity (Normal group) were used. All patients were female. A template model was created by averaging the normal pelvises into a symmetrical and isotropic mesh. Next, 100 homologous models were generated by fitting the pelvic data of each group of patients to the template model. Principal component analysis was performed on the coordinates of each vertex (15,235 vertices) of the pelvic homologous model. In addition, a receiver-operating characteristic (ROC) curve was calculated from the sensitivity of DDH positivity for each principal component, and principal components for which the area under the curve was significantly large were extracted (p<0.05). Finally, which components of the pelvic morphology frequently seen in DDH patients are related to these extracted principal components was evaluated.

The first, third, and sixth principal components showed significantly larger areas under the ROC curves. The morphology indicated by the first principal component was associated with a decrease in coxal inclination in both the coronal and horizontal planes. The third principal component was related to the sacral inclination in the sagittal plane. The sixth principal component was associated with narrowing of the superior part of the pelvis.

The most important factor in the difference between normal and DDH pelvises was the change in the coxal angle in both the coronal and horizontal planes. That is, in the anterior and superior views, the normal pelvis is a triangle, whereas in DDH, it was more like a quadrilateral.

## Linked entities

- **Diseases:** developmental dysplasia of the hip (MONDO:0000158)

## Full-text entities

- **Diseases:** DDH (MESH:D000082602), pelvic deformity (MESH:D034161)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

9 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11146717/full.md

## References

45 references — full list in the complete paper: https://tomesphere.com/paper/PMC11146717/full.md

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Source: https://tomesphere.com/paper/PMC11146717