# Plasma Exchange in Postpartum Hemorrhage (PPH)-Associated Thrombotic Microangiopathy (TMA): A Case Report

## TL;DR

A 28-year-old woman developed a rare blood disorder after childbirth and recovered with plasma exchange therapy, highlighting its potential in similar cases.

## Contribution

This case report adds to the limited evidence on using plasma exchange for postpartum hemorrhage-associated TMA.

## Key findings

- The patient was diagnosed with TMA following a postpartum hemorrhage.
- Plasma exchange therapy led to full recovery of the patient.
- More case reports are needed to better understand treatment efficacy.

## Abstract

Thrombotic microangiopathy (TMA) is a rare yet potentially life-threatening condition. The diagnosis is difficult as there are other conditions presenting with features akin to TMA during the peripartum period such as eclampsia, preeclampsia, hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome, and antiphospholipid syndrome. A 28-year-old woman with no significant past medical history developed TMA following a massive hemorrhage after an emergency cesarean section at 41 weeks of gestation. This case was finally diagnosed as postpartum hemorrhage (PPH)-associated TMA. The patient fully recovered after plasma exchange therapy. We posit the value of accumulating case reports, given that the documentation on the efficacy of plasma exchange in PPH-associated TMA is limited.