# Xenogeneic matrix for basal cell carcinoma reconstruction: a case report

**Authors:** Helmut Hildebrandt, Peer W Kämmerer, Diana Heimes, Amely Hartmann

PMC · DOI: 10.1093/jscr/rjae396 · Journal of Surgical Case Reports · 2024-06-03

## TL;DR

This case report presents a new method using a xenogeneic matrix and platelet-rich fibrin to regenerate tissue after removing basal cell carcinoma, showing promising results.

## Contribution

The paper introduces a novel tissue regeneration protocol using a xenogeneic collagen matrix and platelet-rich fibrin for post-surgical reconstruction.

## Key findings

- The protocol demonstrated efficacy and predictability in soft tissue regeneration.
- The technique offers simple handling and minimal resource requirements.
- It may reduce donor site morbidity and patient comorbidities after surgery.

## Abstract

This case report introduces an innovative approach for tissue regeneration post-total excision of basal cell carcinoma utilizing a xenogeneic collagen matrix coupled with injectable platelet-rich fibrin. The clinical outcome underscores the efficacy and predictability of this protocol in soft tissue regeneration. While further investigation on a larger patient cohort is warranted to fully elucidate its effects and advantages, this technique holds promise in streamlining surgical procedures following excision of extraoral neoplasms. Notably, its simple handling, minimal resource requirements, and potential to mitigate donor site morbidity and patient comorbidities post-surgery signify its value in clinical practice.

## Linked entities

- **Diseases:** basal cell carcinoma (MONDO:0005341)

## Full-text entities

- **Diseases:** extraoral neoplasms (MESH:D009369), basal cell carcinoma (MESH:D002280)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

10 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11146217/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC11146217/full.md

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Source: https://tomesphere.com/paper/PMC11146217