# Zinner Syndrome in Young Adult Males: A Case Series and Literature Review

**Authors:** Praveen K Sharma, Polaka Yashaswinii, Arun Aram, Karpagam RK, Sakthi Ganesh Subramonian

PMC · DOI: 10.7759/cureus.59552 · 2024-05-02

## TL;DR

This paper reports three cases of Zinner Syndrome in young adult males and discusses the diagnosis, treatment, and outcomes.

## Contribution

The novelty lies in presenting a rare syndrome in young adult males and emphasizing its clinical management.

## Key findings

- Three young males were diagnosed with Zinner Syndrome through imaging techniques like USG, CT, and MRI.
- Surgical management led to symptom resolution and improved quality of life for the patients.
- The paper highlights the diagnostic challenges and long-term outcomes of Zinner Syndrome.

## Abstract

Zinner syndrome (ZS) is a highly uncommon congenital or developmental urogenital anomaly characterized by the triumvirate of unilateral renal agenesis or dysplasia, ipsilateral ejaculatory duct obstruction, and ipsilateral seminal vesicle cyst. We present three cases of ZS in a 21-year-old male, a 20-year-old male, and a 24-year-old male. The diagnostic evaluation revealed unilateral renal agenesis associated with hypertrophy of the ipsilateral seminal vesicle with cystic changes on investigation by ultrasonography (USG), computed tomography (CT), and magnetic resonance imaging (MRI). The patients underwent surgical management, resulting in symptom resolution and enhanced quality of life. This case report highlights the diagnostic challenges, management options, and long-term outcomes for patients with ZS.

## Linked entities

- **Diseases:** Zinner Syndrome (MONDO:0100109)

## Full-text entities

- **Diseases:** renal agenesis or dysplasia (MESH:C536482), congenital or developmental urogenital anomaly (MESH:D014564), unilateral renal agenesis (MESH:D000075529), hypertrophy of the ipsilateral seminal vesicle (MESH:C537244), ejaculatory duct obstruction (MESH:D002779), ZS (MESH:D013577)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11144581/full.md

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Source: https://tomesphere.com/paper/PMC11144581