Double Trouble: A Case Report on the Surgical Management of Dual Intracranial Metastases

TL;DR

This case report describes the surgical treatment of a patient with two brain metastases from breast cancer, highlighting the challenges and outcomes of managing such complex cases.

Contribution

The novelty lies in presenting a detailed clinical case of dual intracranial metastases managed with modern surgical techniques and neuronavigation.

Findings

The patient underwent successful gross total resection of a second metastatic lesion in the left parietal lobe.

The surgical approach using neuronavigation and microsurgical techniques resulted in no postoperative complications.

The patient's symptoms improved post-surgery, and she was discharged after five days.

Abstract

Intracranial metastasis disease (IMD) has proven to be a frequent secondary occurrence, usually for primary cancers such as lung, breast, and melanoma, which have a high possibility of metastasizing to the brain. Due to the reasons listed above, treatment and early diagnosis are incredibly challenging. In the past decade, medicine has developed much better imaging solutions and radiological and surgical approaches, increasing the postoperative survival prognosis and achieving more time-efficient results. It is still exceptionally difficult to be able to prevent what type of metastasis a patient might develop other than by using the tumor type or subtype. We present a case of a 51-year-old female patient entering the Neurosurgical Clinic at the University Hospital “St. Ivan Rilski” for operative treatment of a second metastatic lesion located on the left parietal lobe in January 2024. She had previously had an operative resection of an initial lesion located on the left temporal lobe in December 2023. Her medical history began in 2015 when her first diagnosis was a breast carcinoma, followed by operative treatment and radio-, chemo-, and targeted therapy. In 2020, due to metastases located in the bones, she had to undergo another treatment with chemotherapy as well as have a total hysterectomy done as a result of another metastasis. The patient did not provide any family history, nor did she confirm any past or current allergies to foods, drugs, etc. Under general inhalation anesthesia, the patient was placed in a park bench position to the right and had a Mayfield head holder applied. Through a left parietal craniotomy and neuronavigation, a tumor formation was revealed with the characteristic of a secondary lesion. A gross total resection was achieved through a microsurgical technique. Postoperatively, there were no further complications observed in the patient, and she was discharged on day five from the hospital with relief of her symptoms.

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