# ANCA-associated systemic vasculitis initially mimicking peripheral neuropathy in an elderly woman

**Authors:** Xiaojie He, Yaqing Wang, Xiaodong Li

PMC · DOI: 10.12669/pjms.40.5.9070 · Pakistan Journal of Medical Sciences · 2024-05-01

## TL;DR

A rare immune condition called ANCA-associated vasculitis can initially appear as nerve damage, leading to possible misdiagnosis.

## Contribution

This case report highlights the uncommon presentation of AASV as peripheral neuropathy in an elderly patient.

## Key findings

- AASV can initially mimic peripheral neuropathy, leading to diagnostic challenges.
- Early recognition and treatment of AASV are crucial for better patient outcomes.

## Abstract

Anti-neutrophil cytoplasmic antibodies (ANCA)-associated systemic vasculitis (AASV) is a rare systemic immunological condition that predominantly impacts small arteries, veins, and capillaries, often leading to kidney damage and pulmonary injury. It is important to note that individuals primarily presenting with peripheral neuropathy (PN) are uncommon in AASV, which can result in significant misdiagnosis or undiagnosed cases. The severity and location of PN can vary among patients. In this article, we present a case of an AASV patient initially showing signs of PN. This case highlights the significance of considering AASV as a potential cause of unexplained neurological symptoms. Timely identification and proper treatment are essential for improving the survival rate and functional prognosis of AASV patients.

## Linked entities

- **Diseases:** peripheral neuropathy (MONDO:0003620)

## Full-text entities

- **Diseases:** PN (MESH:D010523), AASV (MESH:D056647), systemic immunological condition (MESH:D007153), kidney damage (MESH:D007674), neurological symptoms (MESH:D009461), ANCA-associated systemic vasculitis (MESH:D056648), pulmonary injury (MESH:D055370)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC11140351/full.md

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Source: https://tomesphere.com/paper/PMC11140351