# Virtual tumor mapping and margin control with 3-D planning and navigation

## TL;DR

This paper reviews how 3D virtual mapping and navigation technologies can improve head and neck cancer treatment by enabling precise surgery and radiation planning.

## Contribution

The paper introduces novel approaches for integrating 3D virtual tumor data and molecular findings into treatment and follow-up processes.

## Key findings

- Virtual 3D patient data improves precision in frozen section procedures during surgery.
- Postoperative tumor reconstruction enhances radiation therapy planning.
- Integration of molecular data into virtual tumor models aids postoperative treatment.

## Abstract

Computer technology–based treatment approaches like intraoperative navigation and intensity-modulated radiation therapy have become important components of state of the art head and neck cancer treatment. Multidirectional exchange of virtual three-dimensional patient data via an interdisciplinary platform allows all medical specialists involved in the patients treatment to take full advantage of these technologies. This review article gives an overview of current technologies and future directions regarding treatment approaches that are based on a virtual, three-dimensional patient specific dataset: storage and exchange of spatial information acquired via intraoperative navigation allow for a highly precise frozen section procedure. In the postoperative setting, virtual reconstruction of the tumor resection surface provides the basis for improved radiation therapy planning and virtual reconstruction of the tumor with integration of molecular findings creates a valuable tool for postoperative treatment and follow-up. These refinements of established treatment components and novel approaches have the potential to make a major contribution to improving the outcome in head and neck cancer patients.