# Turmeric extract gel and honey in post-cesarean section wound healing: A preliminary study

**Authors:** Andi Nilawati Usman, Sartini Sartini, Risfah Yulianti, Melani Kamsurya, Agriyaningsih Oktaviana, Zafitri Nulandari, Dinah Inrawati Agustin, Fendi Fendi, Arfa Nasrine, Maulana Yusuf Alkandahri

PMC · DOI: 10.12688/f1000research.134011.1 · F1000Research · 2023-09-01

## TL;DR

This study found that applying Trigona honey twice daily accelerated wound healing after cesarean sections in rats compared to turmeric gel and a control group.

## Contribution

The study introduces Trigona honey as a potentially effective complementary therapy for post-cesarean wound healing.

## Key findings

- Trigona honey applied twice daily resulted in the fastest wound healing in rats.
- Turmeric extract gel at 50% and 75% concentrations healed wounds by days 12 and 15, respectively.
- All treatments showed better healing than the control group.

## Abstract

Background: Delivery by cesarean section (SC) increases the risk of a surgical site infection (SSI). Therapy from health services and complementary therapy reduce the risk of infection and accelerate the wound-healing process. This study compared wound healing after SC with a turmeric extract gel and original Trigona honey.

Methods: Female white rats (
Rattus novergicus) with pre- and post-testing and a control group were included in this experiment, which was conducted in June-July 2022. The test animals were 56 female white rats, 2-4 months old, weighing 150–350 g. The treatment group was divided into three subgroups with application of 50% and 75% turmeric extract gel and Trigona honey. The turmeric was given twice daily, and the honey was divided into two applications of twice a day and once a day. Wounds were assessed using the Reeda Scale.

Results: The fastest wound healing occurred in the group given Trigona honey twice daily. Redness, ecchymosis, and edema disappeared in this group on day 9 (score 0), and granulation tissue formed on day 9. The group that was administered 50% and 75% turmeric gel extract and Trigona honey once a day healed by days 12 and 15, respectively; all three of these interventions were better than the control group.

Conclusions: Administering Trigona honey twice daily was more effective for accelerating wound healing than the 50% or 75% turmeric extract gel. Original Trigona honey has the potential to be a post-SC wound healing agent.

## Full-text entities

- **Diseases:** ecchymosis (MESH:D004438), Wounds (MESH:D014947), edema (MESH:D004487), SSI (MESH:D013530), infection (MESH:D007239)
- **Chemicals:** Trigona honey (-)
- **Species:** Rattus norvegicus (brown rat, species) [taxon 10116]

## Full text

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## References

27 references — full list in the complete paper: https://tomesphere.com/paper/PMC11137484/full.md

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Source: https://tomesphere.com/paper/PMC11137484