This paper is marked retracted in the scholarly record (OpenAlex). Interpret its findings with caution.
RETRACTION: LINC01224 accelerates malignant transformation via MiR‐193a‐5p/CDK8 axis in gastric cancer
TL;DR
This retracted study claimed that the LINC01224 gene promotes gastric cancer through a specific molecular pathway involving MiR-193a-5p and CDK8.
Contribution
The paper proposed a novel mechanism involving LINC01224, MiR-193a-5p, and CDK8 in gastric cancer progression.
Findings
LINC01224 was reported to accelerate malignant transformation in gastric cancer.
The MiR-193a-5p/CDK8 axis was suggested to mediate this effect.
Data irregularities led to the retraction of the study.
Abstract
RETRACTION: H. Sun, J. Yan, G. Tian, X. Chen, W. Song, “LINC01224 accelerates malignant transformation via MiR‐193a‐5p/CDK8 axis in gastric cancer,” Cancer Medicine 10, no. 4 (2021): 1377‐1393, https://doi.org/10.1002/cam4.3726. The above article, published online on 2 March 2021, in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor‐in‐Chief, Stephen Tait, and John Wiley and Sons Ltd. Following publication, concerns were raised by third parties regarding the origin of figure 10A. Several scientific irregularities and unexpected similarities between an instrument in this figure and figures from other papers by unrelated author groups were found. The authors had initially contacted the journal requesting to withdraw their article due to errors presented in their data. However, the authors did not provide further details and did not…
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Taxonomy
TopicsFerroptosis and cancer prognosis · MicroRNA in disease regulation · Circular RNAs in diseases
RETRACTION: H. Sun, J. Yan, G. Tian, X. Chen, W. Song, “LINC01224 accelerates malignant transformation via MiR‐193a‐5p/CDK8 axis in gastric cancer,” Cancer Medicine 10, no. 4 (2021): 1377‐1393, https://doi.org/10.1002/cam4.3726.
The above article, published online on 2 March 2021, in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor‐in‐Chief, Stephen Tait, and John Wiley and Sons Ltd. Following publication, concerns were raised by third parties regarding the origin of figure 10A. Several scientific irregularities and unexpected similarities between an instrument in this figure and figures from other papers by unrelated author groups were found. The authors had initially contacted the journal requesting to withdraw their article due to errors presented in their data. However, the authors did not provide further details and did not respond to our invitation to comment on the additional concerns raised, or provide the original, unmodified figures. The editors have lost confidence in the data and conclusions of this study.