# Hemolysis, Elevated Liver Enzymes and Low Platelet Count Syndrome Complicated by Disseminated Intravascular Coagulation and Posterior Reversible Encephalopathy Syndrome: A Case Report

**Authors:** Bhavana V Waghmare, Shubhada Jajoo, Dharmesh J Patel, Shazia Mohammad, Shaikh Muneeba

PMC · DOI: 10.7759/cureus.59250 · 2024-04-29

## TL;DR

A pregnant woman developed a rare and severe condition involving blood clotting and neurological issues, requiring complex medical care.

## Contribution

This case report highlights the management challenges of HELLP syndrome complicated by coagulation and neurological issues during pregnancy.

## Key findings

- The patient exhibited HELLP syndrome, disseminated intravascular coagulation, and PRES during pregnancy.
- Management required a multidisciplinary approach due to the complexity of the patient's condition.
- The case emphasizes the importance of early recognition and tailored treatment in rare pregnancy-related complications.

## Abstract

A 22-year-old pregnant woman was transferred from an external medical facility after experiencing an eclamptic seizure linked to hemolysis, elevated liver enzymes and low platelet count syndrome (HELLP) syndrome, and posterior reversible encephalopathy syndrome (PRES). Her situation was further complicated by intrauterine fetal demise and disseminated intravascular coagulation, necessitating a comprehensive multidisciplinary approach. This report details the diagnostic process and challenges in managing this complex patient with diverse medical requirements. Emphasis is placed on the observed hemostatic abnormalities, and we delineate the nuances in our approach compared to managing a similar condition in a nonpregnant patient. Heightened awareness among healthcare professionals is imperative for prompt diagnosis and effective intervention in such uncommon neurological complications during pregnancy.

## Linked entities

- **Diseases:** HELLP syndrome (MONDO:0008585), disseminated intravascular coagulation (MONDO:0001243), posterior reversible encephalopathy syndrome (MONDO:0044033), eclampsia (MONDO:0001754)

## Full-text entities

- **Diseases:** Hemolysis (MESH:D006461), Elevated Liver Enzymes (MESH:D017359), Disseminated Intravascular Coagulation (MESH:D004211), PRES (MESH:D054038), hemostatic abnormalities (MESH:D020141), Low Platelet Count Syndrome (MESH:D009845), neurological complications (MESH:D002493), intrauterine fetal demise (MESH:D005313), eclamptic seizure (MESH:D012640)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC11134473/full.md

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Source: https://tomesphere.com/paper/PMC11134473