# A Case of Nasal Glial Heterotopia That Can Be Misdiagnosed as Storiform Patterned Sclerotic Fibroma/Collagenoma

## TL;DR

A 4-year-old child's nasal lesion was diagnosed as nasal glioma, a rare condition that can resemble other fibrous tumors and requires specific tests for accurate identification.

## Contribution

Highlights the importance of immunohistochemical testing to distinguish nasal glioma from collagen-rich fibromas.

## Key findings

- Nasal glioma can mimic collagenoma or Gardner's fibroma histologically.
- Immunohistochemistry revealed S100 and GFAP positivity in the glial component.
- Accurate diagnosis requires considering nasal glioma in sclerotic, storiform-patterned lesions.

## Abstract

Objective: Nasal glioma, also known as nasal glial heterotopia, is a rare tumor-like lesion that often affects newborns or infants with no hereditary predisposition.

Case Report: A 4-year-old child with a growth on the nasal dorsum since birth was diagnosed with nasal glial heterotopia/nasal glioma. The lesion showed a sclerotic fibroma/collagenoma-like storiform pattern with entrapped glial tissue that was S100 and GFAP positive.

Conclusion: When a biopsy of the nasal dorsum demonstrates sclerotic microscopic findings with a storiform pattern, nasal glioma should be considered before making a diagnosis in the collagen-rich tissue spectrum (collagenoma or Gardner's fibroma), and an immunohistochemical panel should be requested to demonstrate the presence of an unrecognized light microscopically visible glial component.