# Unusual Multiple Recurrences of Soft Tissue Giant Cell Tumors in a Patient Above 60 Years

**Authors:** Wazzan ALjuhani, Raed Qeretli, Faisal Alhabradi, Fay A Alotaibi

PMC · DOI: 10.7759/cureus.59195 · Cureus · 2024-04-28

## TL;DR

A 63-year-old woman experienced multiple recurrences of a rare soft tissue tumor after initial treatment, highlighting the need for careful follow-up to prevent metastasis.

## Contribution

This case report highlights the unusual recurrence pattern of GCT-ST in an elderly patient, emphasizing the need for further research and vigilant follow-up.

## Key findings

- A 63-year-old woman had a recurrence of GCT-ST nine months after complete tumor excision.
- The case suggests that older patients may face a higher risk of aggressive disease progression and multiple recurrences.
- The etiology of recurrence remains unclear, underscoring the importance of patient follow-up to prevent metastasis.

## Abstract

Primary giant cell tumors of soft tissues (GCT-ST) are rare neoplasms that share histopathological and immunohistochemical characteristics with osseous giant cell tumors. While GCT-ST generally exhibits a benign progression and can affect individuals of various ages, older patients may face a higher risk of recurrence and aggressive disease progression. In this case report, we present the case of a 63-year-old woman who experienced recurrent GCT-ST nine months after the complete excision of an initially localized tumor. Despite the mainstay treatment of GCT-ST being tumor-free margin surgical excision, this case demonstrates the occurrence of recurrences. The etiology of recurrence in GCT-ST remains unclear, highlighting the need for further studies and careful patient follow-up to prevent potential complications such as lung metastasis or widespread metastasis. Thus, this report aims to raise awareness of these tumors and emphasize the importance of diligent patient follow-up to facilitate early identification and management, thereby preventing potential complications such as lung or widespread metastasis.

## Full-text entities

- **Diseases:** lung metastasis (MESH:D009362), GCT-ST (MESH:D005870), neoplasms (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC11131142/full.md

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Source: https://tomesphere.com/paper/PMC11131142