# Proactive risk stratification and low-risk penicillin allergy delabeling by an antimicrobial stewardship pharmacist

## TL;DR

This paper shows that a pharmacist can help safely remove incorrect penicillin allergy labels from patients, improving antibiotic use.

## Contribution

Pharmacist-led delabeling of low-risk penicillin allergies is feasible without allergy specialist involvement.

## Key findings

- Most patients with penicillin allergy histories were found to be low-risk for delabeling.
- Pharmacists can perform risk stratification and drug challenges independently.
- This approach expands access to allergy delabeling beyond allergy specialist services.

## Abstract

Penicillin (PCN) allergy delabeling is an important component of antimicrobial stewardship; however, widespread implementation has lagged. We found that most patients had low-risk PCN allergy histories eligible for delabeling without skin testing. Pharmacist-led risk stratification and drug challenge expanded access to delabeling independently from an Allergy/Immunology service.