# A Rare Case of Undifferentiated Pleomorphic Cardiac Sarcoma

**Authors:** Taulant Gishto, Leonard Simoni, Andi Kacani, Silvia Methoxha, Alessia Mehmeti

PMC · DOI: 10.7759/cureus.59183 · Cureus · 2024-04-28

## TL;DR

A rare case of undifferentiated cardiac sarcoma was successfully treated with surgery and chemotherapy, resulting in complete remission.

## Contribution

This case report highlights a rare and challenging diagnosis of undifferentiated pleomorphic cardiac sarcoma with a successful treatment outcome.

## Key findings

- A cardiac mass was identified in the left atrium and confirmed as undifferentiated sarcoma via histopathology.
- The patient achieved complete remission six months after surgery and chemotherapy with no recurrence.
- Cardiac sarcomas are rare and difficult to diagnose due to non-specific symptoms.

## Abstract

We present a case of a patient with a four-month history of gradual-onset dyspnea and generalized body weakness. During the clinical evaluation, a mass was found in the left atrium. Coronary angiography was performed and showed normal coronary arteries. We proceeded with a complete surgical excision of the tumoral mass, and histopathology confirmed it as undifferentiated cardiac sarcoma. Six months after the surgical intervention and adjuvant chemotherapy, the patient is in complete remission, with no evidence of a recurrence of the malignant pathology. Cardiac sarcoma is a rare clinical finding and a diagnostic and therapeutic challenge due to its numerous non-specific clinical presentations.

## Linked entities

- **Diseases:** cardiac sarcoma (MONDO:0003354)

## Full-text entities

- **Diseases:** undifferentiated cardiac sarcoma (MESH:D008228), Cardiac Sarcoma (MESH:D006331), tumoral mass (MESH:C536030), dyspnea (MESH:D004417), weakness (MESH:D018908)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11130600/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC11130600/full.md

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Source: https://tomesphere.com/paper/PMC11130600