# Thrombotic Storm: A Case of Multiple Concurrent Thrombosis Secondary to Cocaine Use

**Authors:** Ramayee Nadarajan, Muhammad Areeb Ashfaq, Hajira Z Malik, Siva Parcha

PMC · DOI: 10.7759/cureus.59164 · Cureus · 2024-04-27

## TL;DR

A 49-year-old woman developed multiple blood clots after a large cocaine use, leading to serious complications in her heart and abdomen.

## Contribution

This case highlights the rare but severe concurrent thrombosis associated with cocaine use.

## Key findings

- Cocaine use led to left ventricular mural thrombus and mesenteric artery ischemia.
- The patient also had renal and splenic infarcts.
- Anticoagulation treatment caused retroperitoneal hematoma.

## Abstract

Cocaine abuse is known to have deleterious effects on multiple organ systems. Its effects on the cardiovascular system are well-established in the literature. The presence of a left ventricular thrombus (LVT) is a well-recognized complication of an anterior myocardial infarction, especially in patients with aneurysmal formation. There is a paucity of reports where cocaine use and LVT are associated with myocardial infarction and mesenteric ischemia simultaneously. Our patient is a 49-year-old female, who presented to our institution after ingesting a large volume of cocaine. She complained of abdominal pain, chest pain, and was eventually found to have a left ventricular mural thrombus with concomitant superior mesenteric artery ischemia, and renal and splenic infarcts. Administration of therapeutic anticoagulation resulted in the development of retroperitoneal hematoma resulting in a therapeutic dilemma.

## Linked entities

- **Chemicals:** cocaine (PubChem CID 2826)
- **Diseases:** myocardial infarction (MONDO:0005068)

## Full-text entities

- **Diseases:** mesenteric ischemia (MESH:D065666), myocardial infarction (MESH:D009203), renal and splenic infarcts (MESH:D013159), anterior myocardial infarction (MESH:D056988), artery ischemia (MESH:D007511), abdominal pain (MESH:D015746), aneurysmal formation (MESH:D058426), chest pain (MESH:D002637), retroperitoneal hematoma (MESH:D006406), Cocaine abuse (MESH:D019970), LVT (MESH:D013927)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11129872/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC11129872/full.md

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Source: https://tomesphere.com/paper/PMC11129872