# Second primary common bile duct neuroendocrine tumor after 10 years in a patient with rectal adenocarcinoma: A case report

**Authors:** Saba Ebrahimian, Sakineh Soleimani Varaki, Farid Nasr Esfahani

PMC · DOI: 10.22088/cjim.15.2.360 · Caspian Journal of Internal Medicine · 2024-01-01

## TL;DR

A patient with a history of rectal cancer developed a second primary bile duct neuroendocrine tumor 10 years later, highlighting the need for early detection of new cancers.

## Contribution

The paper presents a rare clinical case emphasizing the importance of treating second primary cancers as new diagnoses.

## Key findings

- A 58-year-old man with a history of rectal cancer developed a neuroendocrine tumor in the bile duct.
- The patient underwent surgery and was discharged in good condition after treatment.
- The case underscores the need for vigilance in detecting second primary cancers.

## Abstract

With the improvement of cancer treatment methods and increased life expectancy of patients, the prevalence of second primary cancers has gradually increased.

In the present study, the case was a 58-year-old man diagnosed with rectal adenocarcinoma and underwent chemotherapy and neoadjuvant radiotherapy 10 years ago. After 5 years, he underwent a lobectomy due to lung metastasis. At the research time, he presented with itching; in ERCP, a 16-millimeter hypoechoic lesion was detected, and an FNA biopsy was performed, indicating malignancy. The patient underwent Whipple surgery, and pathology revealed a well-differentiated neuroendocrine tumor. He was discharged in good general condition.

This article emphasized the necessity of early detection and diagnosis of second primary cancer, as well as acting as if it was primary cancer to treat.

## Linked entities

- **Diseases:** rectal adenocarcinoma (MONDO:0002169), neuroendocrine tumor (MONDO:0019496)

## Full-text entities

- **Diseases:** neuroendocrine tumor (MESH:D018358), rectal adenocarcinoma (MESH:D000230), lung metastasis (MESH:D009362), cancer (MESH:D009369), itching (MESH:D011537), common bile duct neuroendocrine tumor (MESH:D003138), primary (MESH:D010538)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11129070/full.md

## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC11129070/full.md

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Source: https://tomesphere.com/paper/PMC11129070