# Editorial: Advancing therapeutic strategies: exploring ABC transporters and chemicals affecting their expression and function for disease treatment

**Authors:** Guido Veit, Michinori Matsuo, Tsukasa Okiyoneda

PMC · DOI: 10.3389/fphar.2024.1423979 · Frontiers in Pharmacology · 2024-05-13

## Full-text entities

- **Genes:** IL17A (interleukin 17A) [NCBI Gene 3605] {aka CTLA-8, CTLA8, IL-17, IL-17A, IL17, ILA17}, ABCC4 (ATP binding cassette subfamily C member 4 (PEL blood group)) [NCBI Gene 10257] {aka MOAT-B, MOATB, MRP4}, ABCG2 (ATP binding cassette subfamily G member 2 (JR blood group)) [NCBI Gene 9429] {aka ABC15, ABCP, BCRP, BMDP, CD338, CDw338}, ABCB1 (ATP binding cassette subfamily B member 1) [NCBI Gene 5243] {aka ABC20, CD243, CLCS, ENPAT, GP170, MDR1}, SLC26A4 (solute carrier family 26 member 4) [NCBI Gene 5172] {aka DFNB4, EVA, PDS, TDH2B}, DNAH8 (dynein axonemal heavy chain 8) [NCBI Gene 1769] {aka ATPase, SPGF46, hdhc9}, TNF (tumor necrosis factor) [NCBI Gene 7124] {aka DIF, IMD127, TNF-alpha, TNFA, TNFSF2, TNLG1F}, CFTR (CF transmembrane conductance regulator) [NCBI Gene 1080] {aka ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR}, ABCA3 (ATP binding cassette subfamily A member 3) [NCBI Gene 21] {aka ABC-C, ABC3, EST111653, LBM180, SMDP3}
- **Diseases:** inflammation (MESH:D007249), CF (MESH:D003550), monogenetic disorders (MESH:D009358)
- **Chemicals:** elexacaftor (MESH:C000629074), phosphomolybdate (MESH:C003125), ivacaftor (MESH:C545203), tezacaftor (MESH:C000625213), HCO3 - (MESH:D001639), FR3 (-), 4-phenylbutyrate (MESH:C075773), lipid (MESH:D008055), Trikafta (MESH:C000706587), nucleotide (MESH:D009711), antimony (MESH:D000965)
- **Species:** Homo sapiens (human, species) [taxon 9606]
- **Mutations:** F508del
- **Cell lines:** Sf9 — Spodoptera frugiperda (Fall armyworm), Spontaneously immortalized cell line (CVCL_0549)

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC11128889/full.md

## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC11128889/full.md

---
Source: https://tomesphere.com/paper/PMC11128889