# Giant Cell Tumor of the Clivus in a 19-Year-Old Male Presenting With Doubling of Vision: A Case Report

**Authors:** Ma. Regina D Matabang, Paul Vincent A Opinaldo

PMC · DOI: 10.7759/cureus.59117 · Cureus · 2024-04-26

## TL;DR

A 19-year-old male with a rare clival giant cell tumor experienced persistent symptoms despite treatment, emphasizing the need for long-term monitoring and additional therapies.

## Contribution

This case report adds to the limited literature on clival giant cell tumors and highlights the challenges in their management.

## Key findings

- The patient's clival GCT progressed despite partial excision and adjuvant radiation therapy.
- Symptoms persisted, underscoring the need for prompt and continued treatment strategies.
- Long-term surveillance is crucial for managing such rare and aggressive tumors.

## Abstract

Giant cell tumor (GCT) of the skull is an extremely rare condition, accounting for less than one percent of all bone GCTs. Clival GCT is even rarer, with only 25 cases documented to date. It generally follows a benign course; however, due to its location and vascularity, it can be locally aggressive. Complete resection of GCT in this location may be challenging, resulting in residual tumors. In this paper, we report a case of a 19-year-old male who presented with a chronic headache later accompanied by diplopia and was noted to have a mass spanning the sella and the clivus on cranial imaging. The histopathology report of the excised mass revealed findings compatible with GCT of the bone. Most GCTs remain stable in the first two years after initial treatment. However, four months after its partial excision, the clival GCT continued to progress. The patient underwent adjuvant radiation therapy, yet symptoms persisted. This profile highlights the crucial role of long-term surveillance and prompt adjuvant radiation therapy and chemotherapy.

## Linked entities

- **Diseases:** Giant cell tumor (MONDO:0002171)

## Full-text entities

- **Diseases:** Clival GCT (MESH:D005870), diplopia (MESH:D004172), tumors (MESH:D009369), GCT of the bone (MESH:D018212), headache (MESH:D006261), bone GCTs (MESH:D001847)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

6 references — full list in the complete paper: https://tomesphere.com/paper/PMC11128768/full.md

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Source: https://tomesphere.com/paper/PMC11128768