# Hydralazine-Induced Antineutrophilic Cytoplasmic Antibody (ANCA)-Associated Vasculitis Presenting as Crescentic Glomerulonephritis

## TL;DR

A patient developed a rare kidney condition linked to an autoimmune reaction after long-term use of hydralazine, a blood pressure medication.

## Contribution

This case report highlights hydralazine as a potential cause of ANCA-associated vasculitis leading to crescentic glomerulonephritis.

## Key findings

- Hydralazine therapy was associated with the development of ANCA-associated vasculitis.
- The patient presented with crescentic glomerulonephritis as a result of the autoimmune reaction.
- This case underscores the need to consider drug-induced vasculitis in patients with unexplained kidney issues.

## Abstract

Hydralazine is a vasodilator medication commonly used for treating hypertension. While generally well-tolerated, in rare cases it can induce autoimmune reactions, including anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis. This case report presents a patient who developed ANCA-associated vasculitis resulting in crescentic glomerulonephritis (CrGN) following long-term hydralazine therapy, highlighting the importance of considering this rare adverse effect in patients with unexplained renal decline.