# A Case Report of Shingles Vaccine as a Cause of Third Nerve Palsy: A Novel Etiology

**Authors:** Jorge Sanchez, Hector DeLosSantos, Mrunalini Dandamudi, Lorenza Freddo, Guido A Macchiavello

PMC · DOI: 10.7759/cureus.59086 · Cureus · 2024-04-26

## TL;DR

This paper reports a rare case where the shingles vaccine may have caused third nerve palsy, a novel and unexpected side effect.

## Contribution

The paper introduces a new potential side effect of the shingles vaccine: third nerve palsy.

## Key findings

- A case of third nerve palsy following the shingles vaccine is reported.
- This is the first known association between the zoster vaccine and third nerve palsy.

## Abstract

Vaccines are biological preparations widely used to provide acquired immunity against various life-threatening organisms and prevent severe complications of different infections. Vaccines typically demonstrate a high level of safety with minimal adverse effects. Nevertheless, it is crucial to enhance awareness when a potential new side effect emerges, as exemplified in the case discussed ahead. Despite the rarity of independent third nerve palsy occurrences, its association with the zoster vaccine remains unprecedented.

## Linked entities

- **Diseases:** shingles (MONDO:0005609)

## Full-text entities

- **Diseases:** infections (MESH:D007239), Third Nerve Palsy (MESH:D015840), zoster (MESH:D006562)

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC11128331/full.md

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11128331/full.md

## References

21 references — full list in the complete paper: https://tomesphere.com/paper/PMC11128331/full.md

---
Source: https://tomesphere.com/paper/PMC11128331