# Comparison Between Urine Dipstick and Microscopic Examination Urinalysis With Urine Culture to Evaluate the Sensitivity and Specificity for Each in Diagnosing Urinary Tract Infection in Qassim Region, Saudi Arabia

**Authors:** Hana S Almuhanna, Ali M Alhojelan, Yasir A Al Rusayni, Muhannad A Almohanna, Hatem M AlDhalea, Abdullah A Aljulajil

PMC · DOI: 10.7759/cureus.59069 · Cureus · 2024-04-26

## TL;DR

This study compares urine dipstick and urinalysis tests for diagnosing urinary tract infections in Saudi Arabia's Qassim region.

## Contribution

The study provides region-specific sensitivity and specificity data for urine dipstick and urinalysis in UTI diagnosis.

## Key findings

- Urine dipstick had a sensitivity of 0.79 and specificity of 0.39 for UTI diagnosis.
- Urinalysis showed high sensitivity (0.95) but poor specificity (0.21).
- E. coli was the most common organism isolated in positive urine cultures.

## Abstract

Background: Urinalysis is the most popular test for evaluating emergency room patients with possible urinary tract infections (UTIs). Due to their speed and inexpensive cost, urine dipsticks are frequently performed in the Emergency Room. Although a urine dipstick test may be less expensive and time-saving than a laboratory study, it may not be accurate. The study evaluated the sensitivity and specificity of urine dipstick and microscopic urinalysis with a urine culture.

Methodology: A prospective, observational study was conducted on adults who visited the Emergency Department at King Fahd Specialist Hospital in Buraydah and reported having dysuria, urine urgency, or frequency, as well as suprapubic or costovertebral angle soreness. Patients who could not give a trustworthy history, had symptoms of vaginal discharge, or had taken antibiotics within the previous 72 hours were excluded.

Results: One hundred fifty-three urine samples were collected and examined using urinalysis and dipstick. In addition, 113 (73.86%) of 153 urine samples exhibited no growth in urine culture. With a count of nine, Escherichia coli (E. coli) was the most often isolated organism among the positive cultures (5.88%). Klebsiella pneumoniae was the second most common in our sample with eight (5.23%). The urine dipstick was shown to have an overall sensitivity of 0.79, specificity of 0.39, positive productive value (PPV) of 0.30, and negative productive value (NPV) of 0.85. Urinalysis exhibited a high sensitivity of 0.95 and a poor specificity of 0.21.

Conclusion: Our study showed that urine dipsticks may be more beneficial than urinalysis for ruling out urinary tract infections (UTIs), while urinalysis may be more helpful in verifying their presence.

## Linked entities

- **Diseases:** urinary tract infection (MONDO:0005247)
- **Species:** Escherichia coli (taxon 562), Klebsiella pneumoniae (taxon 573)

## Full-text entities

- **Diseases:** dysuria (MESH:D053159), soreness (MESH:D063806), UTIs (MESH:D014552), vaginal discharge (MESH:D019522)
- **Species:** Escherichia coli (E. coli, species) [taxon 562], Homo sapiens (human, species) [taxon 9606], Klebsiella pneumoniae (species) [taxon 573]

## Full text

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## References

21 references — full list in the complete paper: https://tomesphere.com/paper/PMC11128248/full.md

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Source: https://tomesphere.com/paper/PMC11128248