# The Effect of Chitosan Gel 15% in the Surgical Treatment of Stage III Periodontitis: A Case Report of Two Cases

**Authors:** Ahmad M Alnada, Wael H Almahdi, Mohamad A Fawaz

PMC · DOI: 10.7759/cureus.58965 · 2024-04-24

## TL;DR

This case report shows that using 15% chitosan gel during surgery for periodontitis improved gum health by reducing pocket depth and bleeding in two patients over six months.

## Contribution

Demonstrates the effectiveness of 15% chitosan gel in periodontal surgery for stage III periodontitis in a clinical case setting.

## Key findings

- Probing depth decreased by 3.30±0.27 mm after six months of treatment.
- Bleeding on probing was reduced from 84.61% to 0% after six months.
- Chitosan gel application showed positive outcomes in open flap debridement for periodontal pockets.

## Abstract

Periodontal diseases are widely spread, particularly in adults. Chitosan has non-toxicity and biocompatibility properties, as it has been studied in many studies in various surgical applications. This case report includes two female patients (aged 23 and 48) who were treated by the application of Chitosan gel 15% during open flap debridement in an aggregate of 26 periodontal pockets. Several clinical measurements were evaluated (probing depth, gingival recession, and bleeding on probing) for the treated periodontal pockets, between two periods, the first in baseline and then after six months. The results showed a reduction in probing depth of (3.30±0.27) after six months. The bleeding on probing also decreased from 84.61% to 0%. This case report concluded that the application of Chitosan gel 15% reduced pocket depth and bleeding on probing when applied in open flap debridement.

## Linked entities

- **Chemicals:** Chitosan (PubChem CID 129662530)
- **Diseases:** Periodontitis (MONDO:0005076)

## Full-text entities

- **Diseases:** gingival recession (MESH:D005889), pockets (MESH:D005888), Periodontal diseases (MESH:D010510), toxicity (MESH:D064420), III (MESH:C537189), Periodontitis (MESH:D010518), bleeding (MESH:D006470)
- **Chemicals:** Chitosan Gel (-), Chitosan (MESH:D048271)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11126890/full.md

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Source: https://tomesphere.com/paper/PMC11126890