# Cocaine-Induced Chronic Bowel Ischemia Manifesting As Small Bowel Obstruction

**Authors:** Iraklis Perysinakis, Georgios Saridakis, Miltiadis Giannarakis, Georgia Kritikou, Eelco de Bree

PMC · DOI: 10.7759/cureus.58964 · 2024-04-24

## TL;DR

A young woman developed a rare case of small bowel obstruction due to chronic mesenteric ischemia caused by cocaine use.

## Contribution

This paper presents a rare clinical case linking chronic cocaine use to small bowel obstruction via mesenteric ischemia.

## Key findings

- Cocaine-induced chronic mesenteric ischemia can lead to small bowel obstruction.
- Excessive intestinal wall fibrosis was observed as a result of chronic ischemia in the patient.

## Abstract

Cocaine represents one of the most frequently used recreational drugs worldwide. Cocaine-related disorders mostly affect the nervous and cardiovascular system, although gastrointestinal complications are not negligible and sometimes life-threatening. The most common gastrointestinal manifestations of cocaine abuse are ulceration, infarction, perforation, ischemic enterocolitis, and rarely hemorrhage, with mesenteric ischemia being the underlying pathophysiological mechanism. Herein, we report a rare case of cocaine-induced small bowel obstruction in a young female patient, caused by chronic mesenteric ischemia and excessive intestinal wall fibrosis.

## Linked entities

- **Chemicals:** cocaine (PubChem CID 2826)

## Full-text entities

- **Diseases:** Small Bowel Obstruction (MESH:D007409), gastrointestinal complications (MESH:D005767), hemorrhage (MESH:D006470), Bowel Ischemia (MESH:D007511), fibrosis (MESH:D005355), cocaine abuse (MESH:D019970), ischemic enterocolitis (MESH:D004760), infarction (MESH:D007238), mesenteric ischemia (MESH:D065666)
- **Chemicals:** Cocaine (MESH:D003042)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11126889/full.md

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Source: https://tomesphere.com/paper/PMC11126889