# Essential thrombocythemia: nutritional management in weight loss and malnutrition

**Authors:** Isabela de Souza da Costa Brum, Julia Goncalves, Mariana Zanchetta, Bruna Xerém, Renata Lanziani, Marcia Haiut, Masato Hada, Alexandre Gustavo Apa, Karen Cordovil

PMC · DOI: 10.11604/pamj.2024.47.93.32594 · 2024-02-28

## TL;DR

This paper discusses how nutritional management can help patients with essential thrombocythemia combat weight loss and malnutrition.

## Contribution

The paper introduces a systematic approach to nutritional intervention for managing weight loss in essential thrombocythemia patients.

## Key findings

- Patients with essential thrombocythemia may experience gastrointestinal and metabolic issues leading to weight loss.
- Cytokine stimulation may disrupt appetite and metabolic control, contributing to body mass loss.
- Systematic nutritional intervention is essential to improve patient compliance and nutritional status.

## Abstract

Essential thrombocythemia is the category of myeloproliferative syndromes, generally characterized by a group of clonal stem cell diseases that present a disturbance in the growth of one or more sets of hematopoietic cells. All long clinical treatment, patients may experience gastrointestinal disorders and other metabolic processes that can lead to weight loss and malnutrition. Cytokine is involved in the control of appetite, digestive, and metabolic processes in the body, it can be assumed that increased stimulation could impair the control of these processes leading to loss of body mass. Effective and systematic nutritional intervention is required to ensure patient compliance with treatment and improved nutritional status.

## Linked entities

- **Diseases:** essential thrombocythemia (MONDO:0005029)

## Full-text entities

- **Diseases:** Essential thrombocythemia (MESH:D013920), myeloproliferative syndromes (MESH:D009196), weight loss (MESH:D015431), malnutrition (MESH:D044342), loss of body mass (MESH:C536030), cell diseases (MESH:D009081), gastrointestinal disorders (MESH:D005767)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC11126749