Challenges and Uncertainties in the Diagnosis of Cardiac Amyloidosis: A Case Report
Alia A Ibrahim, Mohammed Gaffar Mohammed, Haitham B Elmasharaf, Ibrahim Y Osman, Nagoud M Ali
TL;DR
This case report highlights the challenges in diagnosing cardiac amyloidosis and emphasizes key signs in echocardiography that can lead to early detection.
Contribution
The paper identifies specific echocardiographic red flags that can prompt further investigation for cardiac amyloidosis.
Findings
Cardiac amyloidosis can present with heart failure and arrhythmia, often misdiagnosed initially.
Echocardiography can reveal key indicators that suggest the presence of cardiac amyloidosis.
Early recognition of these signs can improve diagnostic accuracy and patient outcomes.
Abstract
Amyloidosis is the condition when starch-like misfolded proteins form insoluble fibrils that deposit in tissues and cause dysfunction. Cardiac amyloidosis occurs due to the deposition of amyloid fibrils at the cardiac level and is an important cause of heart failure. This case reveals a patient with significant heart failure and arrhythmia, which later on turned out to be caused by cardiac amyloidosis. While regarded as a rare disease in practice, in retrospect, there are a lot of signs and imaging indicators, particularly in echocardiography that warrant an investigation of cardiac amyloidosis. In this case review, red flags in echocardiography that should endorse further testing for underlying cardiac amyloidosis are highlighted.
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsAmyloidosis: Diagnosis, Treatment, Outcomes · Parathyroid Disorders and Treatments · Sarcoidosis and Beryllium Toxicity Research