Independent and Joint Effects of Prenatal Incense-Burning Smoke Exposure and Children’s Early Outdoor Activity on Preschoolers’ Obesity

TL;DR

Exposure to incense smoke during pregnancy and low outdoor activity in early childhood may increase obesity risk in preschoolers.

Contribution

This study is the first to investigate the independent and combined effects of prenatal incense-burning smoke exposure and early outdoor activity on preschool obesity.

Findings

Prenatal incense-burning smoke exposure increased obesity risk (AOR = 1.13).

Lower outdoor activity frequency or duration in early childhood was linked to higher obesity risk.

Combined effects of smoke exposure and low outdoor activity further increased obesity risk.

Abstract

Incense burning is a significant source of indoor air pollution in many Asian regions. There is emerging evidence that maternal prenatal exposure to incense-burning smoke may be a risk factor for childhood obesity. We aimed to extend this new line of research by investigating the independent and joint effect of incense-burning smoke exposure, and children’s outdoor activity in early life, on preschoolers’ obesity. A total of 69,637 mother–child dyads were recruited from all kindergartens in the Longhua District of Shenzhen, China. Information on sociodemographic characteristics, maternal exposure to incense-burning smoke (IBS) during pregnancy, and frequency and duration of outdoor activity at the age of 1–3 years was collected by a self-administered questionnaire. In addition, the heights and weights of the children were measured by the research team. Logistic regression models and cross-over analyses were conducted to investigate the independent and combined effects of maternal exposure to incense-burning smoke during pregnancy and children’s early outdoor activity on obesity in preschoolers. We found that prenatal exposure to incense-burning smoke increased the risk of the presence of obesity in preschoolers’ (AOR = 1.13, 95% CI = 1.03–1.23). Additionally, lower frequencies (<3 times/week) or shorter durations (<60 min/time) of outdoor activity from the age of 1–3 years were significantly associated with the presence of obesity, with AORs of 1.24 (95% CI =1.18–1.32) and 1.11 (95% CI = 1.05–1.17), respectively. Furthermore, the cross-over analysis showed that prenatal exposure to IBS combined with a lower frequency of early outdoor activity (AOR = 1.47, 95% CI = 1.31–1.66) or a shorter duration of outdoor activity during ages of 1–3 years (AOR = 1.22, 95% CI = 1.07–1.39) increased the risk of obesity in preschoolers. Finally, additive interactions between prenatal exposure to IBS and postnatal outdoor activity on obesity were identified. Our study indicates that maternal exposure to incense-burning smoke during pregnancy and early lower postanal outdoor activity may independently and jointly increase the risk of obesity among preschoolers.

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