# Clinical Consequences of Unreconstructed Pelvic Defect Caused by Osteosarcoma with Subsequent Progressive Scoliosis in a Pediatric Patient—Case Report

**Authors:** Sławomir Zacha, Katarzyna Kotrych, Wojciech Zacha, Jowita Biernawska, Arkadiusz Ali, Dawid Ciechanowicz, Paweł Ziętek, Daniel Kotrych

PMC · DOI: 10.3390/children11050607 · Children · 2024-05-19

## TL;DR

This case report describes a rare pediatric patient with both osteosarcoma of the pelvis and adolescent idiopathic scoliosis, successfully treated with no recurrence after nine years.

## Contribution

The first reported case of pelvis osteosarcoma coexisting with adolescent idiopathic scoliosis.

## Key findings

- The patient underwent successful treatment with no tumor recurrence over nine years.
- The case highlights unique challenges in managing scoliosis in oncologic patients.
- A scoping review confirmed the novelty of this combined condition.

## Abstract

Osteosarcoma is the most common primary malignant bone tumor in children and adolescents. The standard and most effective treatment is wide resection of the tumor combined with neoadjuvant chemotherapy. Adolescent idiopathic scoliosis (AIS) is a genetically determined three-dimensional spinal deformity, which occurs in teenage patients and is mostly progressive. The basic management strategy is surgical treatment when the curve exceeds 50 degrees. However, the indications are different in oncologic patients. The aim of this study was to describe a case of adolescent scoliosis with osteosarcoma of the pelvis. The authors conducted a scoping review using PubMed and Embase to analyze the state of knowledge. The presented paper is the first report of pelvis osteosarcoma coexisting with adolescent idiopathic scoliosis. Treatment for this complex case finished with very good results, with no recurrence observed during the nine-year follow-up.

## Linked entities

- **Diseases:** osteosarcoma (MONDO:0002623), adolescent idiopathic scoliosis (MONDO:0005488)
- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Diseases:** tumor (MESH:D009369), Pelvic Defect (MESH:D034161), AIS (OMIM:181800), spinal deformity (MESH:D013122), Scoliosis (MESH:D012600), Osteosarcoma (MESH:D012516), oncologic (MESH:D000072716), bone tumor (MESH:D001859)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

8 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11120253/full.md

## References

23 references — full list in the complete paper: https://tomesphere.com/paper/PMC11120253/full.md

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Source: https://tomesphere.com/paper/PMC11120253