# Safety and efficacy of a feed additive consisting of an essential oil derived from the leaves of Cymbopogon nardus (L.) Rendle (citronella oil) for use in all animal species (FEFANA asbl)

**Authors:** Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Mojca Durjava, Maryline Kouba, Marta López‐Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Fernando Ramos, Roberto Edoardo Villa, Ruud Woutersen, Andrew Chesson, Josef Schlatter, Johannes Westendorf, Yvette Dirven, Paola Manini, Birgit Dusemund

PMC · DOI: 10.2903/j.efsa.2024.8790 · EFSA Journal · 2024-05-23

## TL;DR

This paper evaluates the safety and effectiveness of citronella oil in animal feed for various species and concludes it is generally safe for animals, consumers, and the environment.

## Contribution

The study provides new safety thresholds for citronella oil in animal feed across multiple species.

## Key findings

- Citronella oil is safe for long-living and reproductive animals at specified concentrations.
- The additive is considered of no concern for short-living animals at higher concentrations.
- The essential oil is irritant to skin and eyes and a dermal sensitiser.

## Abstract

Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of citronella oil obtained from the leaves of Cymbopogon nardus (L.) Rendle, when used as a sensory additive for all animal species. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concluded that citronella oil from C. nardus is of low concern for long‐living and reproductive animals at the use levels in complete feed of 3.5 mg/kg for laying hens and rabbits, 6 mg/kg for sows and dairy cows, 9.5 mg/kg for sheep/goats and horses, 2.0 mg/kg for cats and 10 mg/kg for dogs. For short‐living animals (species for fattening), the additive was considered of no concern at concentrations of 18 mg/kg in chickens for fattening, 24 mg/kg in turkeys for fattening, 20 mg/kg for piglets, pigs for fattening, veal calves (milk replacer), cattle for fattening, sheep/goats for meat production, horses for meat production and rabbits for meat production, and 30 mg/kg for salmonids. The conclusions were extrapolated to physiologically related minor species. For any other species, the additive is considered of low concern at 2.0 mg/kg complete feed. The use of citronella oil in animal feed is expected to be of no concern for the consumers and for the environment. The essential oil under assessment should be considered as irritant to skin and eyes and as a dermal sensitiser. When handling the essential oil, exposure of unprotected users to methyleugenol may occur. Therefore, to reduce the risk, the exposure of the users should be minimised. Since the leaves of C. nardus and its preparations were recognised to flavour food and its function in feed would be essentially the same as that in food, no further demonstration of efficacy was considered necessary.

## Linked entities

- **Chemicals:** methyleugenol (PubChem CID 7127)
- **Species:** Cymbopogon nardus (taxon 79840)

## Full-text entities

- **Species:** Capra hircus (domestic goat, species) [taxon 9925], Cymbopogon nardus (citronella grass, species) [taxon 79840], Felis catus (cat, species) [taxon 9685], Canis lupus familiaris (dog, subspecies) [taxon 9615], Oryctolagus cuniculus (domestic rabbit, species) [taxon 9986], Ovis aries (domestic sheep, species) [taxon 9940], Sus scrofa (pig, species) [taxon 9823], Meleagris gallopavo (common turkey, species) [taxon 9103], Bos taurus (bovine, species) [taxon 9913], Equus caballus (domestic horse, species) [taxon 9796], Salmonidae (salmonids, family) [taxon 8015], Gallus gallus (bantam, species) [taxon 9031]

## Full text

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## References

56 references — full list in the complete paper: https://tomesphere.com/paper/PMC11112456/full.md

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Source: https://tomesphere.com/paper/PMC11112456